OrienTM

Last updated on Jun 8, 2023
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OrienTM
Release date1999
ImplementationC++
AuthorsLiakopoulos, T., Pasquier, C., and Hamodrakas, S.

OrienTM1 2 is a computer software that utilizes an initial definition of transmembrane segments to predict the topology of transmembrane proteins from their sequence. It uses position-specific statistical information for amino acid residues which belong to putative non-transmembrane segments derived from statistical analysis of non-transmembrane regions of membrane proteins stored in the SwissProt database. Its accuracy compares well with that of other popular existing methods.

  1. Theodore Liakopoulos, Claude Pasquier, Stavros Hamodrakas (1999). OrienTM: A Novel Method to Predict Transmembrane Protein Topology. 21st Conference of the Hellenic Society for Biological Sciences.

    Conference Site

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  2. Theodore Liakopoulos, Claude Pasquier, Stavros Hamodrakas (2001). A Novel Tool for the Prediction of Transmembrane Protein Topology Based on a Statistical Analysis of the SwissProt Database: The OrienTM Algorithm. Protein Engineering.

    PDF DOI Article Link Journal Site

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Computational Biology Protein Structure Prediction
Claude Pasquier
Claude Pasquier
Researcher in Computer Science / Computational Biology

Université côte d’Azur, CNRS, I3S Laboratory, Sophia Antipolis