2

L’essentiel du symposium UCAncer 2021 sur les approches multidisciplinaires de la recherche sur le cancer

Temporal and Sequential Order of Nonoverlapping Gene Networks Unraveled in Mated Female Drosophila

In this study, we reanalyzed available datasets of gene expression changes in female Drosophila head induced by mating. Mated females present metabolic phenotypic changes and display behavioral characteristics that are not observed in virgin females, …

SETMAR Shorter Isoform: A New Prognostic Factor in Glioblastoma

Recent evidence suggests that the chimeric protein SETMAR is a factor of interest in cancer, especially in glioblastoma. However, little is known about the expression of this protein in glioblastoma tissues, and no study has been done to assess if …

Identification of Active Modules in Interaction Networks Using Node2vec Network Embedding

The identification of condition-specific gene sets from transcriptomic experiments is important to reveal regulatory and signaling mechanisms associated with a given cellular response. Statistical approaches using only expression data allow the …

Computational Search of Hybrid Human/SARS-CoV-2 dsRNA Reveals Unique Viral Sequences That Diverge from Those of Other Coronavirus Strains

The role of the RNAi/Dicer/Ago system in degrading RNA viruses has been elusive in mammals in the past, which has prompted authors to think that interferon (IFN) synthesis is essential in this clade, relegating the RNAi defense strategy against viral …

Computational Prediction of miRNA / mRNA Duplexomes at the Whole Human Genome Scale Reveals Functional Subnetworks of Interacting Genes with Embedded miRNA Annealing Motifs

Mining Evolutions of Complex Spatial Objects Using a Single-Attributed Directed Acyclic Graph

Directed acyclic graphs (DAGs) are used in many domains ranging from computer science to bioinformatics, including industry and geoscience. They enable to model complex evolutions where spatial objects (e.g., soil erosion)maymove, (dis)appear,merge …

Computational Search of Hybrid Human/ SARS-CoV-2 dsRNA Reveals Unique Viral Sequences That Diverge from Other Coronavirus Strains

The role of the RNAi/Dicer/Ago system to degrade RNA viruses has been elusive in mammals,which prompted authors to think that interferon (IFN) synthesis is essential in this clade relegatingthe RNAi defense strategy against viral infection as …

Transcriptome-Wide-Scale-Predicted dsRNAs Potentially Involved in RNA Homoeostasis Are Remarkably Excluded from Genes with No/Very Low Expression in All Developmental Stages

RNA interference (RNAi) refers to a conserved posttranscriptional mechanism for the degradation of RNA by short dsRNAs. A genome-wide analysis of mRNAs that are complementary to RNAs of variable length that are transcribed from the full transcriptome …

Prediction of miRNA-disease Associations Using an Evolutionary Tuned Latent Semantic Analysis.

MicroRNAs, small non-coding elements implied in gene regulation, are very interesting biomarkers for various diseases such as cancers. They represent potential prodigious biotechnologies for early diagnosis and gene therapies. However, experimental …